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pentobarbital will decrease the extent or influence of efavirenz by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unfamiliar.pentobarbital will reduce the extent or effect of atogepant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Intently. Advised atogepant dosage with concomi